Trans-Nasal Esophagoscopy (TNE) is the better option, and it works like this: a doctor numbs the nose, inserts a thin, flexible tube — no bigger than a pencil — through the nostril and into the esophagus, removes a bit of tissue for biopsy purposes, takes a few pictures, and pulls the tube back out through the nostril. The patient gets to watch it all on a monitor and gets to depart from the procedure with no ill effects.

Traditional esophagus cancer screening involves a similar tube that is inserted through the mouth. Due to the gag reflex, patients are sedated. While there are often no complications from the procedure itself, the intravenous sedation can cause problems.

“You don’t need those risks to see what’s going on,” says one doctor, who reports that esophageal cancer responds very well when caught early by tools like TNE.q