Archive for the ‘Mouth Cancer’ Category

Scientists have determined that mouth cancer develops in two different ways which dictates the seriousness of the disease. This finding, revealed on Tuesday, could lead to better prevention and treatment. In laboratory experiments with healthy, early, and advanced cancer cells, researchers were able to pinpoint differences in the cells that determined the aggressiveness of the cancer. They found faults in the p53 gene, which stops damaged cells from dividing, and in the p16 gene, which helps regulate and prevent cancer from developing. Both changes are linked to more aggressive tumors. This is first-time evidence that some mouth cancer tumors are more aggressive than others and are unfortunately linked to poor patient survival.

Oral cancer typically stems from pre-cancerous lesions, changes, or patches in the mouth — all of which are early signs of cancer. Recognizing which pre-cancerous changes are more likely to develop into aggressive tumors would allow doctors an insight that could help them prescribe the best treatment.

Smoking, use of chewing tobacco, and heavy alcohol consumption are the leading causes of mouth cancer. And smoking and drinking are a very dangerous combination. Like lung cancer, mouth cancer usually develops in people age 50 or older.


Chemotherapy is a good remedy for killing cancer cells — and I hope every day that it did its job and killed all cancer cells that may have floated away from my original breast cancer tumor. But one not-so-good side effect of this good remedy is the beating that healthy cells take in the process of this life-saving treatment. It will be a red-letter day when chemotherapy can target only cancer cells, while leaving healthy cells unaffected. And this day may be a bit closer for patients in Taiwan who find they are in the early stages of relapse with nasopharynx cancer.

On Wednesday, National Taiwan University Hospital introduced a new high-tech laser procedure — potassium-titanyl-phosphate or KPT — to vaporize cancer cells. Doctors use a small endoscopic camera and easily manipulate the laser to precisely eliminate the cancer cells in the back of the nose and the soft roof of the mouth — without harming healthy cells. The procedure takes roughly 90 minutes and requires a two-day stay in the hospital. This procedure should only be used in the early stages of relapse, though, and first-time cancer patients should still seek chemotherapy. And while those in later stages of relapse can still receive the treatment, it will only relieve discomfort without solving the problem.

To date, there have been 16 successful KPT treatments for this disease that about 1,000 people in Taiwan contract each year.