Cancer cases are expected to more than double between the years 2000 and 2030, says the director of the World Health Organization’s International Agency for Research on Cancer.

This upward climb will occur primarily in poor countries due to an increase in population growth, longer life expectancy, more smoking, and a lack of health care in low and medium-resource countries.

“What’s going to happen between now and 2030 is that the population is going to increase from about 6.5 billion to 8 billion in 2030,” Dr. Peter Boyle reports. “So even if the risks remain constant at each five-year age group, because we’ve got more people around, we’re going to have more cases of cancer.

It’s the unfortunate successes for developed countries over the past 40 years, such as the export of cigarette smoking and alcohol consumption, that have doomed poorer countries, says Boyle.

Consider this definition of doom: By the year 2030, there will be 27 million cases of cancer, 17 million deaths caused by the disease, and 75 million people living with cancer.

Increased intake of vitamin C from the diet, but not from supplements may slash the risk of mouth cancer by 48 percent, says an epidemiological study.

The study, published in the International Journal of Cancer, used data on supplement use and diet for 42,340 men in the Health Professional Follow-Up Study. During the course of the study, 207 oral pre-malignant lesions were documented.

Vitamin C from dietary sources was significantly associated with a reduced risk of mouth cancer, but no association with the vitamin from supplements was found.

Vitamin C is needed to form collagen, a tissue that helps to hold cells together. It’s essential for healthy bones, teeth, gums, and blood vessels. It helps the body absorb iron and calcium, aids in wound healing and contributes to brain function.

You can find high levels of vitamin C in red berries, kiwi, red and green bell peppers, tomatoes, broccoli, spinach, and juices made from guava, grapefruit and orange.

Boise State basketball player Coby Karl, son of Denver Nuggets coach George Karl, had surgery 13 months ago to remove his thyroid after he was diagnosed with papillary carcinoma, a form of treatable cancer. And while Karl received chemotherapy to kill off any lingering cancer cells, he must undergo cancer surgery once again.

Karl, who plans to play in the NABC All-Star game in Atlanta on March 31, will return to Boise on April 2 for surgery to remove cancerous lymph nodes.

The lymph node cancer was identified in January, but Karl, 23, kept his condition private until his team lost to New Mexico State in the Western Athletic Conference tournament semifinals. This ended the Broncos’ season. And now begins Karl’s second go-round with cancer.

Karl was one of last year’s NBA draft hopefuls. He worked out for three teams, including his dad’s team, but eventually withdrew his name from the draft and returned to Boise State for his senior year.

High-fat diet may increase breast cancer risk. According to a large study of middle-age women with a wide range of fat in their diet shows that eating a high-fat diet raises the risk of developing invasive breast cancer. This report in the Journal of the National Cancer Institute, stem from the National Institutes of Health-AARP Diet and Health Study, in which 188,736 postmenopausal women reported detailed information on their diet in the mid-1990s. During an average follow-up of 4.4 years, 3501 women developed breast cancer.

Based on responses to a 124-item “food frequency” questionnaire, researchers found that women who got 40 percent of their calories from fat had about a 15 percent increased risk of developing breast cancer compared with women got 20 percent of their calories from fat. The increased risk of breast cancer associated with a high-fat diet was seen for all types of fat (saturated, monounsaturated and polyunsaturated) and seemed to be confined to women who were not using hormone replacement therapy at the start of the study.

In a commentary on the study, two researchers from Harvard School of Public Health in Boston think that focusing on controlling body fat, rather than fat intake, would be more effective in preventing breast cancer.

The “modest associations” that have been observed between high-fat diets and increased breast cancer risk “stand in sharp contrast to the robust evidence for a strong link between (body fat) and the risk of postmenopausal breast cancer,” write Drs. Stephanie Smith-Warner and Meir Stampfer.

SOURCE: Journal of the National Cancer Institute, March 21, 2007

More research points to the medicinal effects of red wine. Researchers say the consumption of more than three glasses of red wine a week reduced the risk of colon cancer.

Joseph C. Anderson, M.D, and his colleagues at SUNY Stony Brook, compared the drinking habits of 360 red and white wine drinkers with similar lifestyles as part of a study examining the prevalence of colorectal neoplasia.

They found that drinking red wine significantly reduced the risk of colorectal neoplasia by 68 percent, but drinking white wine did not. Researchers suspect that higher concentrations of the compound resveratrol in red wine may provide a protective effect against colon cancer.

The research highlights the potential role of red wine in chemoprevention of colon cancer, but when it comes to proven prevention strategies, doctors say screening for colorectal cancer remains essential and is the most proven preventative measure that individuals can use to reduce their risk of developing this disease.

Screening tests can find precancerous polyps, allowing removal before they turn into cancer.

Colorectal cancer is one of the most detectable, and if found early enough, the most treatable forms of cancer, according to the American College of Gastroenterology.

Doctors prescribing anemia drugs for patients with kidney disease and cancer were urged by the Food and Drug Administration (FDA) on Friday to carefully dispense of these drugs due to an increased risk of death and other serious problems, such as blood clots, strokes, and heart attacks in patients with chronic kidney failure and rapid tumor growth in patients with head and neck cancer who receive doses higher than recommended.

The potentially harmful drugs, sold under than brand names Procrit, Epogen, and Aranesp, are genetically engineered versions of a natural protein, called erythropoietin that increases the number of red blood cells. The drugs, with combined 2006 U.S. sales of $10 billion, are commonly used for patients with certain forms of kidney disease and for those receiving chemotherapy for cancer.

The FDA is adding warnings to the drugs’ labels that will strongly instruct doctors to use the lowest possible dose needed to help patients avoid blood transfusions.

The FDA will also take a close look at how the drugs are marketed, including claims the drugs can improve the quality of life.

A meeting of FDA officials to further discuss this issue, believed to stem from drug overuse by dialysis centers and oncologists who make more money by using more of the drugs. is scheduled for May 10. Recommendations could lead to additional revisions of the drugs’ labels.

He first played on professional football teams, the San Diego Chargers, the Houston Oilers, and the Kansas City Chiefs, and then found fame and fortune in professional wrestling, a sport that landed him in the World Wrestling Federation Hall of Fame.

He is Ernie “Big Cat” Ladd. And on Saturday night, he died of cancer at the age of 68.

Ladd’s battle with cancer began in 2004. It started in his colon and later spread to his stomach and bones.

“The doctor told me I had three-to-six months to live,” Ladd said in 2005. “I told him Dr. Jesus has the verdict on me.”

It seems the great doctor gave Ladd, the 15th player taken in the 1961 AFL draft, more than a few months, proof that numbers are not everything in the game of cancer.

Ladd, almost 6-foot-10 and more than 300 pounds, started making appearances at wrestling events during his football career. He was first a special events referee and then became a wrestler. It was both a knee injury and the lure of the lucrative wrestling industry that ended Ladd’s football career.

“In what other sport can you pick up a $14 pair of boots, $0.59 socks, spend maybe a total of $50, and convert it into $100,000 a year, if you are sharp and train?” Ladd once said. “My intention was to go back to football, but pro wrestling was so good to me.”

Devastating blood born fungal infections that can be lethal for cancer, HIV/AIDS, and organ transplant patients may be treated more successfully, thanks to a new drug delivery method of Amphotericin B developed by researchers at the University of British Columbia in Vancouver. Because the oral form of the drug is easier to administer and cheaper than intravenous delivery more patients would have access to the medicine. Amphotericin B deoxycholate (AmBd) has been the gold standard for the treatment of systemic mycoses for the past 5 decades. The intravenous form of the drug caused severe kidney toxicity as well as serious tissue damage at the intravenous injection site. This research was triggered by clinicians needing a way to kill these fungal infections without risking the patient’s kidney. The new form can be can be taken by mouth with minimal side effects boosting effectiveness and dramatically reducing toxicity.

It was effective in treating Candida albicans an infection prevalent in HIV/AIDS and cancer patients receiving chemotherapy, and can cause symptoms ranging from cough to brain damage. Research funding for this project was provided by the Canadian Institutes of Health Research, Canada’s major agency responsible for funding health research. Composed of 13 Institutes, CIHR provides leadership and support to more than 10,000 health researchers and trainees across Canada.

FRIDAY, March 2 (HealthDay News) — A component of green tea, combined with low doses of the cox-2 inhibitor painkiller Celebrex, may be able to slow prostate cancer growth, according to a U.S. study.

Previous research found that, individually, both the green tea polyphenol epigallocatechin-3-gallate (EGCG), a known antioxidant, and cox-2 inhibitors helped fight prostate cancer in animals.

In this study of cultured human prostate cancer cells and mice, researchers at the University of Wisconsin-Madison found that a combination of EGCG and the cox-2 inhibitor celecoxib (Celebrex) was 15 percent to 28 percent more effective in slowing the growth of cancer cells than either agent alone.

The study, which was funded by the U.S. National Cancer Institute, was published March 1 in the journal Clinical Cancer Research.

“Celecoxib and green tea have a synergistic effect — each triggering cellular pathways that, combined, are more powerful than either agent alone. We hope that a clinical trial could lead to a preventative treatment as simple as tea time,” Hasan Mukhtar, professor of dermatology and a member of the Paul Carbone Comprehensive Cancer Center, said in a prepared statement.

“Prostate cancer typically arises from more than one defect in the cellular mechanics, which means that a single therapeutic might not work fighting a particular cancer long-term. If tests in human trials replicate (the results of this study), we could see a powerful combined therapy that is both simple to administer and relatively cost effective,” Mukhtar said.

Attorney General and Tsawwassen resident Wally Oppal has been diagnosed with prostate cancer, but he says the treatment shouldn’t keep him away from his work for long.

Oppal said he is scheduled to have surgery March 20, and after the initial shock of the diagnosis he is confident about his recovery.

“I play basketball, I lift weights, I don’t smoke, I’m in fairly good health I thought, until they found this lump in a routine checkup,” Oppal said Thursday. “It’s very disconcerting. It’s a shock when you’re told you have cancer, but after you gather your emotional thoughts, you have to get your life together.”

Returning to the legislature after making an announcement in Vancouver about his condition, Oppal said he isn’t feeling any fatigue and doesn’t expect to be off work for long.

“I expect I’ll be a few days away, but I’m going to be working out of my Vancouver office,” the former B.C. Court of Appeal judge said. “I’m going to get a condo very close to it so they can bring me work.”

Oppal was joined at his Vancouver announcement by Premier Gordon Campbell and Tourism Minister Stan Hagen, who had a full recovery after surgery for prostate cancer. He urged older men to overcome their embarrassment and see their doctor for a checkup that includes a digital rectal examination.